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Hulk- Hulk has a regenerative healing factor which at a high enough level of anger surpasses deadpool's. Wolverine can only take on the hulk due to the Adamantium he possesses but if didn't a single punch against a wall would literally smush his head into goop, which would happen to deadpool as he doesn't have sufficient agility like Spiderman he would inevitably eventually get hit and turned into goop.

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